Tabela
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Liverpool | 6 | 4 | 2 | 0 | 15 | 4 | +11 | 14 |
| 2 | Manchester City | 6 | 4 | 1 | 1 | 12 | 1 | +11 | 13 |
| 3 | Chelsea | 6 | 4 | 1 | 1 | 12 | 2 | +10 | 13 |
| 4 | Manchester United | 6 | 4 | 1 | 1 | 13 | 5 | +8 | 13 |
| 5 | Everton | 6 | 4 | 1 | 1 | 12 | 7 | +5 | 13 |
| 6 | Brighton & Hov… | 5 | 4 | 0 | 1 | 7 | 4 | +3 | 12 |
| 7 | West Ham United | 6 | 3 | 2 | 1 | 13 | 8 | +5 | 11 |
| 8 | Aston Villa | 6 | 3 | 1 | 2 | 9 | 7 | +2 | 10 |
| 9 | Brentford | 6 | 2 | 3 | 1 | 8 | 5 | +3 | 9 |
| 10 | Tottenham Hotspur | 5 | 3 | 0 | 2 | 3 | 6 | -3 | 9 |
| 11 | Watford | 6 | 2 | 1 | 3 | 7 | 9 | -2 | 7 |
| 12 | Leicester City | 6 | 2 | 1 | 3 | 7 | 10 | -3 | 7 |
| 13 | Arsenal | 5 | 2 | 0 | 3 | 2 | 9 | -7 | 6 |
| 14 | Crystal Palace | 5 | 1 | 2 | 2 | 5 | 8 | -3 | 5 |
| 15 | Southampton | 5 | 0 | 4 | 1 | 4 | 6 | -2 | 4 |
| 16 | Wolverhampton Wanderers | 5 | 1 | 0 | 4 | 2 | 5 | -3 | 3 |
| 17 | Newcastle United | 6 | 0 | 3 | 3 | 7 | 14 | -7 | 3 |
| 18 | Leeds United | 6 | 0 | 3 | 3 | 6 | 14 | -8 | 3 |
| 19 | Burnley | 6 | 0 | 2 | 4 | 5 | 11 | -6 | 2 |
| 20 | Norwich City | 6 | 0 | 0 | 6 | 2 | 16 | -14 | 0 |
Ostatnie wyniki
| 25.09.2021 | ||
| Brentford | 3 - 3 | Liverpool |
| Watford | 1 - 1 | Newcastle United |
| Leicester City | 2 - 2 | Burnley |
| Leeds United | 1 - 2 | West Ham United |
| Everton | 2 - 0 | Norwich City |
| Manchester United | 0 - 1 | Aston Villa |
| Chelsea | 0 - 1 | Manchester City |
| 19.09.2021 | ||
| Tottenham Hotspur | 0 - 3 | Chelsea |
| West Ham United | 1 - 2 | Manchester United |
| Brighton & Hov… | 2 - 1 | Leicester City |
| 18.09.2021 | ||
| Aston Villa | 3 - 0 | Everton |
| Burnley | 0 - 1 | Arsenal |
| Liverpool | 3 - 0 | Crystal Palace |
| Manchester City | 0 - 0 | Southampton |
| Norwich City | 1 - 3 | Watford |
| Wolverhampton Wanderers | 0 - 2 | Brentford |
| 17.09.2021 | ||
| Newcastle United | 1 - 1 | Leeds United |
| 13.09.2021 | ||
| Everton | 3 - 1 | Burnley |
| 12.09.2021 | ||
| Leeds United | 0 - 3 | Liverpool |
Nadchodzące mecze
| 26.09.2021 | ||
| Southampton | 15:00 | Wolverhampton Wanderers |
| Arsenal | 17:30 | Tottenham Hotspur |
| 27.09.2021 | ||
| Crystal Palace | 21:00 | Brighton & Hov… |
| 02.10.2021 | ||
| Manchester United | 13:30 | Everton |
| Burnley | 16:00 | Norwich City |
| Chelsea | 16:00 | Southampton |
| Leeds United | 16:00 | Watford |
| Wolverhampton Wanderers | 16:00 | Newcastle United |
| Brighton & Hov… | 18:30 | Arsenal |
| 03.10.2021 | ||
| Crystal Palace | 15:00 | Leicester City |
| Tottenham Hotspur | 15:00 | Aston Villa |
| West Ham United | 15:00 | Brentford |
| Liverpool | 17:30 | Manchester City |
| 16.10.2021 | ||
| Watford | 13:30 | Liverpool |
| Manchester City | 16:00 | Burnley |
| Southampton | 16:00 | Leeds United |
| Leicester City | 16:00 | Manchester United |
| Norwich City | 16:00 | Brighton & Hov… |
| Aston Villa | 16:00 | Wolverhampton Wanderers |
| Brentford | 18:30 | Chelsea |